Percutaneous Electrode Ablation System
The CellFX® nsPFA System is a significant advancement in minimally invasive surgical technology. Developed by Pulse Biosciences, the CellFX System utilizes Nanosecond Pulsed Field Ablation (nsPFA) technology to induce natural Regulated Cell Death in cells while minimizing damage on surrounding acellular tissue. This System comprises the state-of-the-art CellFX nsPFA Console and the CellFX nsPFA Percutaneous Electrodes, both of which are integral to delivering this revolutionary treatment.
Indications for Use: The nsPFA™ Percutaneous Electrode System is indicated for ablation of soft tissue in percutaneous, and intraoperative surgical procedures. The nsPFA Percutaneous Electrode System (Percutaneous Electrode) is not indicated for use in cardiac procedures. The nsPFA Percutaneous Electrode System is FDA Cleared for use in the United States only.
Advantages of nsPFA
Non-Thermal Mechanism
Uses ultrafast electrical pulses to induce regulated cell death without heat, minimizing collateral damage to surrounding tissues.
Cellular Specific Action
Targets only cells within the ablation zone, sparing critical acellular structures like vessels, nerves, and connective tissue.
Rapid Tissue Clearance
Delivers quick results with majority of tissue effect occurring within first two weeks, and natural removal of ablated cells without leaving necrotic tissue.
What is Nanosecond Pulsed Field Ablation (nsPFA™)?
Nanosecond Pulsed Field Ablation (nsPFA™) is a nonthermal technology that uses ultra-short electrical pulses to target and ablate cellular structures while sparing acellular tissues. Unlike thermal methods, nsPFA™ energy creates nanopores in cell membranes, allowing ions like calcium to enter and disrupt vital cell organelles, leading to regulated cell death (RCD). This precise approach ensures complete ablation of target cells with minimal impact on surrounding tissues.